is it possible?

is it possible for a first gen s-10 to lay frame on 20s with stock A-arms. ive heard some say yes and some no. thanks for any help

Yes if you cut your arms.

even with drop spindles

you'll need drop spindles, re-work the lower control arms where the humps are, notch for tie rods, and possibly re-angle the upper balljoints depending on the tire size.

Yes you will have to dehump the LCAs and change the angle of the upper ball joint.